|Universe||Destroy All Humans! Universe|
|Eye color||Black (reflective)|
Orthopox 13 is the mastermind and Crypto's trusty mentor, as well as the thirteenth incarnation of the original Orthopox. He won medals in almost every Furon science fair he attended and was a truly hard worker of the Furon race. He is best known for surviving the war with the Blisk as well as commanding the Cryptosporidium clones in collecting Human DNA from their brain stems for a full decade, from 1959 to 1969.
Orthopox 13 was finally slain in 1969 when the KGB missile targets and subsequently destroys the mothership he had been residing in. However, he had sufficient time either before or after the attack to download his consciousness into a Furon hologram projector, allowing him to technically continue living as Holopox.