Pantora had a democratically elected government, presided over by the Pantoran Assembly which was in turn led by the Chairman. During the Clone Wars, the manipulative Chi Cho at the time ruled over Pantora as chairman. The moon was represented in Galactic Senate by the young female Senator Riyo Chuchi. An influential moon, Pantora was able to request and receive a Republic outpost within its system as a measure of protection against the CIS forces during the Clone Wars.
Initially thought to be the only inhabited world in the system, Pantora orbited the ice world of Orto Plutonia, which was a protectorate of the Pantorans and—unknown to them—a home to a Talz colony. When the existence of Talz was discovered, the planet was granted sovereignty—though Chairman Cho fiercely opposed the measure and started a war with the Talz. However, Senator Chuchi intervened at the behest of the Pantoran Assembly and, in respect of the Talz's wishes to be left alone, she recalled the Pantoran and Republic presence from the ice world and returned to Pantora. Not long after, Baron Notluwiski Papanoida became the new Chairman of Pantora.
Later in the war, Pantora was blockaded by the Trade Federation under the command of Lott Dod to force Pantora to join the Separatists. The blockade led to violent riots and calls to join the CIS in desperation. Papanoida managed to overcome the crisis after his daughters were kidnapped and held as leverage, with the help of Senator Chuchi and Ahsoka Tano, who aided him in their rescue. Chuchi successfully negotiated with the Trade Federation ambassador to end the blockade and resume trade relations after she threatened to blackmail him and expose his alliance with the Separatists.