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Talarian Hook Spiders are non-sapient arachnoid beings whose legs are half a meter in length, according to Chief O'Brien.
During the 24th century, the Zayran System became infected with these spiders and O'Brien was called to reroute an emitter array on Zayra IV. After encountering 20 of the arachnoids in a single Jefferies tube, he was actually able to face his arachnophobia and from there on stopped being afraid of spiders.