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According to the Doctor, the Flood is a patient and intelligent pathogen that has time as an ally. This thing is an extreme danger to any life-form in the galaxy because it takes one drop in a world's water supply for it to take control of a planet. However, like other threats in the galaxy it has many weaknesses and flaws. Electricity is a good weapon because it and water are a bad combination. Nuclear explosions are also good since it was demonstrated by the Martian colony. Freezing temperatures are also injuring against it since ice imprisons them. After the destruction of the base however there is a chance of it returning due to the amount of glaciers on Mars. It is possible that it might be on other worlds.
Doctor Who, The Specials episode 3 - The Waters of Mars